DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function.
Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest.
Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.
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DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function.
Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest.
Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.
Imprint | Kluwer Academic / Plenum Publishers |
Country of origin | United States |
Series | Biotechnology Intelligence Unit, 7 |
Release date | September 2003 |
Availability | Expected to ship within 12 - 17 working days |
First published | September 2003 |
Editors | Dan Luo, W. Mark Saltzman |
Dimensions | 235 x 155 x 14mm (L x W x T) |
Format | Hardcover |
Pages | 135 |
Edition | 2003 ed. |
ISBN-13 | 978-0-306-47701-0 |
Barcode | 9780306477010 |
Categories | |
LSN | 0-306-47701-7 |