Statistical Genetics - Gene Mapping Through Linkage and Association (Paperback)

The mapping of the human genome means it is now feasible to conduct large genome-wide linkage and association studies for complex behaviors and diseases. This means that the focus of research is now to identify the genes responsible for such conditions. Identifying these genes will help readers to understand why some people are prone to mental and physical disease, improve early diagnosis, and eventually could lead to treatments.Statistical Genetics is an advanced textbook focusing on conducting genetic linkage and association analysis in the post-genomic era. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website that provides supplementary material and links to downloadable software.